Cancer Drug Toxicities and Anaesthesia
نویسنده
چکیده
Dr de Souza is a Senior Staff specialist in the Department of Medical Oncology at the St George and Sutherland Hospitals in Sydney. He has an interest in translational research and clinical trials. He also has a laboratory interest in urological cancers and drug development. Currently, Dr. de Souza is the Head of Clinical Trials for the CRCT (Consortium for Rational Cancer Therapeutics), a collaboration of 4 major teaching hospital cancer centres in Sydney and the Illawarra.
منابع مشابه
Evaluation of several drug combinations for intraperitoneal anaesthesia in adult male rats
The objective of this study was to evaluate several drug combinations for intraperitoneal anaesthesia in laboratory rats. Following dose determination of anaesthetics in a pilot study, 45 healthy adult male rats were randomly assigned in 9 treatment groups and received propofol (alone or in combination with xylazine, midazolam, or ketamine) or ketamine (in combination with xylazine, midazolam, ...
متن کاملNear-fatal drug toxicities in newborn babies: A Case Series
Background: Neonates are highly vulnerable to drug toxicities because of their age-related limitations in drug metabolisms and renal excretion. Lack of the knowledge and/or education for medical professionals about the right dose administration and the lack of neonate-specific formulations are the additional dilemmas. Cases Presentation: Here, we reported six neonates presented with severe ...
متن کاملNUDT15 genetic variants and 6-mercaptopurine intolerance in pediatric acute lymphoblastic leukemia: an updated review
Acute lymphoblastic leukemia (ALL) accounts for nearly 30% of pediatric cancers. The maintenance treatment for ALL comprises daily oral 6-mercaptopurine (6-MP) and weekly methotrexate (MTX). 6-MP is a purine analog that can significantly improve the long-term survival of ALL patients. Despite more than 90% of 5-year survival of childhood ALL in developed countries, treatment interruption due to...
متن کاملنقش سلکوکسیب همراه با کمورادیاسیون در کاهش موکوزیت و سایر عوارض حاد بیماران با کانسرهای پیشرفته سر و گردن
Background: Chemo-radiotherapy-induced oral mucositis represents a therapeutic challenge frequently encountered in cancer patients. This side effect causes significant morbidity and may delay or interruption of treatment plan, cyclo-oxygenase 2 (COX2) is an inducible enzyme primarily expressed in inflamed and tumoral tissues. COX-2 inhibitors have shown promise to reduce chemoradiation induce t...
متن کاملAnaesthesia and anti-cancer chemotherapeutic drugs.
PURPOSE OF REVIEW This is a review of anti-cancer chemotherapeutic drugs, describing their actions, interactions, and toxicity with a particular focus on the relevance for the anaesthetist. RECENT FINDINGS Anti-cancer chemotherapeutics have a vast array of adverse effects, some of which, i.e. cardiac and pulmonary toxicity, are of particular anaesthesiological relevance. Recently it has been ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008